I remember the little clear IV looked like saline and the nurse said, "Your insurance is getting billed $75,000 for this, so lay back and enjoy" - that was one of many expensive treatments, I was very lucky to have good insurance.
I was told the rapid debulking was because the first infusion I got was a targeted drug that specifically found and destroyed the cancer cells.
The follow up chemo was R-CHOP (Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone), and my understanding this regimen is still being used.
My dad just went through lymphoma treatment using R-CHOP in 2024. It really is like a miracle. He felt like shit for a day after treatment (actually he felt like shit for one entire day, three days after treatment because he was pumped so full of steroids). Otherwise no real side effects.